Long-term outcome of patients with atrial myxoma after surgical intervention: analysis of 403 cases.
J Geriatr Cardiol
; 16(4): 338-343, 2019 Apr.
Article
en En
| MEDLINE
| ID: mdl-31105754
ABSTRACT
OBJECTIVE:
To assess long-term survival and late cardiovascular events in patients with atrial myxoma after surgical intervention.METHODS:
Retrospective analysis of 403 patients undergoing resection of atrial myxoma from January 2002 to December 2016 was conducted with a median follow-up period of 4.5 (range 0.5-15) years.RESULTS:
The cross-clamp time and cardiopulmonary bypass times were 41.1 ± 21.4 and 65.2 ± 27.3 min, respectively. A diagnosis of myxoma was histopathologically confirmed in all cases. The early in-hospital mortality rate was 0.7% (n = 3). During the follow-up period, tumor recurrence occurred in six patients and cerebral infarction in nine. There were 48 (11.9%) patients with late onset atrial fibrillation (AF). By multivariate analysis, age (HR = 1.05, 95% CI 1.02-1.09, P < 0.001), left atrial diameter (HR = 1.23, 95% CI 1.08-1.36, P = 0.012), and mitral valve surgery (HR = 1.17, 95% CI 1.05-1.29, P = 0.027) were independent predictors of late onset AF. Twenty-one (5.2%) patients died during the follow-up period. Advanced age (HR = 1.07, 95% CI 1.04-1.10, P = 0.003) and multiple surgical procedures (HR = 1.18, 95% CI 1.06-1.29, P = 0.012) were significantly associated with overall mortality.CONCLUSIONS:
Atrial myxoma can be resected with good long-term survival. Late onset AF is common after surgery in patients with atrial myxoma. Advanced age, left atrial diameter, and mitral valve surgery were independent predictors of outcomes.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
J Geriatr Cardiol
Año:
2019
Tipo del documento:
Article
País de afiliación:
China