Enrichment of cancer stem-like cells by the induction of epithelial-mesenchymal transition using lentiviral vector carrying E-cadherin shRNA in HT29 cell line.

Saltanatpour, Zohreh; Johari, Behrooz; Alizadeh, Akram; Lotfinia, Majid; Majidzadeh-A, Keivan; Nikbin, Behrooz; Kadivar, Mehdi

Saltanatpour, Zohreh; Johari, Behrooz; Alizadeh, Akram; Lotfinia, Majid; Majidzadeh-A, Keivan; Nikbin, Behrooz; Kadivar, Mehdi.

Afiliación

Saltanatpour Z; Department of Molecular Medicine, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Johari B; Genetics Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran.
Alizadeh A; Department of Medical Biotechnology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Lotfinia M; Department of Tissue Engineering and Applied Cell Sciences, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Majidzadeh-A K; Core Research Lab, Kashan University of Medical Sciences, Kashan, Iran.
Nikbin B; Genetics Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran.
Kadivar M; Department of Molecular Medicine, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.

J Cell Physiol ; 234(12): 22935-22946, 2019 12.

Article en En | MEDLINE | ID: mdl-31111504

Asunto(s)

Cadherinas/genética; Neoplasias del Colon/genética; Transición Epitelial-Mesenquimal/genética; Células Madre Neoplásicas/metabolismo; Antígeno AC133/genética; Cadherinas/antagonistas & inhibidores; Neoplasias del Colon/patología; Regulación Neoplásica de la Expresión Génica; Vectores Genéticos/genética; Células HT29; Humanos; Receptores de Hialuranos/genética; Lentivirus/genética; Invasividad Neoplásica/genética; Invasividad Neoplásica/patología; Células Madre Neoplásicas/patología; ARN Interferente Pequeño/genética

Palabras clave

E-cadherin; cancer stem cells (CSCs); cancer therapy.; epithelial-mesenchymal transition (EMT); lentiviral vector

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Cadherinas / Neoplasias del Colon / Transición Epitelial-Mesenquimal Límite: Humans Idioma: En Revista: J Cell Physiol Año: 2019 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Estados Unidos

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