Contamination status of bisphenol A and its analogues (bisphenol S, F and B) in foodstuffs and the implications for dietary exposure on adult residents in Zhejiang Province.
Food Chem
; 294: 160-170, 2019 Oct 01.
Article
en En
| MEDLINE
| ID: mdl-31126448
ABSTRACT
An effective method has been developed for the simultaneous determination of four bisphenols (bisphenol A, S, F and B) in various foodstuffs. The contaminants were extracted by QuEChERS-based strategy and subjected to ion-exchange solid-phase extraction for further clean-up. The critical variables were screened by Plackett-Burman design and then optimized by central composite design. Under the optimized conditions, satisfactory accuracy (recoveries 76%-116%) and precision (RSDsâ¯<â¯12%) were achieved. The established method was then used to assess the contamination status of 379 real samples. Bisphenol A was demonstrated to be the predominant bisphenol with highest incidence (79.7%) and average concentration (14.3⯵g/kg). The positive rates (mean concentration) of bisphenol S, F and B were 37.7% (1.6⯵g/kg), 26.9% (1.4⯵g/kg) and 0.0% (not detected), respectively. Finally, the daily dietary intakes of ∑4bisphenolsfor adult residents were estimated (55.9-76.1â¯ng/kgâ¯bw/day) according to the contamination concentrations and the daily recommended intakes.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fenoles
/
Sulfonas
/
Compuestos de Bencidrilo
/
Análisis de los Alimentos
Límite:
Humans
Idioma:
En
Revista:
Food Chem
Año:
2019
Tipo del documento:
Article