Variation of spacer type and topology of phenyl moiety in 2-pyridone core of 4-oxo-3-<i>N</i>-methylcytisine; effect of synthesized compounds on rat's behavior in conditioned passive avoidance reflex (CPAR) test.

Tsypysheva, Inna; Petrova, Polina; Koval'skaya, Alena; Lobov, Alexander; Sapozhnikova, Tatyana; Makara, Nina; Gabdrakhmanova, Svetlana; Zarudii, Felix

Variation of spacer type and topology of phenyl moiety in 2-pyridone core of 4-oxo-3-N-methylcytisine; effect of synthesized compounds on rat's behavior in conditioned passive avoidance reflex (CPAR) test.

Tsypysheva, Inna; Petrova, Polina; Koval'skaya, Alena; Lobov, Alexander; Sapozhnikova, Tatyana; Makara, Nina; Gabdrakhmanova, Svetlana; Zarudii, Felix.

Afiliación

Tsypysheva I; Laboratory of bioorganic chemistry and catalysis, Ufa Institute of Chemistry UFRC RAS, Ufa, Russian Federation.
Petrova P; Laboratory of physicochemical methods of analysis, Ufa Institute of Chemistry UFRC RAS, Ufa, Russian Federation.
Koval'skaya A; Laboratory of bioorganic chemistry and catalysis, Ufa Institute of Chemistry UFRC RAS, Ufa, Russian Federation.
Lobov A; Laboratory of physicochemical methods of analysis, Ufa Institute of Chemistry UFRC RAS, Ufa, Russian Federation.
Sapozhnikova T; Laboratory of bioorganic chemistry and catalysis, Ufa Institute of Chemistry UFRC RAS, Ufa, Russian Federation.
Makara N; Laboratory of physicochemical methods of analysis, Ufa Institute of Chemistry UFRC RAS, Ufa, Russian Federation.
Gabdrakhmanova S; Laboratory of bioorganic chemistry and catalysis, Ufa Institute of Chemistry UFRC RAS, Ufa, Russian Federation.
Zarudii F; Laboratory of physicochemical methods of analysis, Ufa Institute of Chemistry UFRC RAS, Ufa, Russian Federation.

Nat Prod Res ; 35(2): 207-215, 2021 Jan.

Article en En | MEDLINE | ID: mdl-31140310

Asunto(s)

Alcaloides/química; Reacción de Prevención/efectos de los fármacos; Reflejo/efectos de los fármacos; Aldehídos/química; Alcaloides/síntesis química; Alcaloides/farmacología; Animales; Condicionamiento Clásico; Evaluación Preclínica de Medicamentos/métodos; Masculino; Piridonas/química; Quinolizinas/síntesis química; Quinolizinas/química; Quinolizinas/farmacología; Ratas; Relación Estructura-Actividad

Palabras clave

(-)-cytisine; 4-oxo-3-N-methylcytisine; conditioned passive avoidance reflex (CPAR); quinolizidine alkaloids

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Reflejo / Reacción de Prevención / Alcaloides Límite: Animals Idioma: En Revista: Nat Prod Res Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google