[Benefits of Molecular Analyses in Thyroid Carcinoma]. / Nutzen molekularer Analysen beim Schilddrüsenkarzinom.
Praxis (Bern 1994)
; 108(8): 535-540, 2019 Jun.
Article
en De
| MEDLINE
| ID: mdl-31185849
ABSTRACT
Benefits of Molecular Analyses in Thyroid Carcinoma Abstract. The widespread access to neck ultrasonography has led to high detection rates of thyroid nodules, whose vast majority will remain clinically silent. In daily practice it is a challenge to filter out the thyroid nodules that require medical attention. This is usually achieved by a combination of sonomorphologic criteria and fine-needle aspiration cytology. In recent years, there is a trend toward deescalation in diagnostic and therapeutic measures for thyroid nodules. Some authors even advocate active surveillance instead of surgical approaches for very low-risk thyroid carcinoma. This approach requires an accurate assessment of the malignant potential of each thyroid nodule. As recent studies have allowed better understanding of molecular pathogenesis of thyroid cancer, the mutational profile of thyroid nodules has emerged as a new tool for assessment of thyroid nodules. Its exact clinical application in daily routine remains, however, unclear.
Palabras clave
Carcinome thyroïdien; Gen-Expressions-Classifier; Next-Generation-Sequencing; Schilddrüsenkarzinom; Thy; Thyroid carcinoma; classificateur d'expression génique; gene expression classifier; molecular testing; molekulare Testung; next-generation sequencing; séquençage de nouvelle génération; tests moléculaires
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias de la Tiroides
/
Nódulo Tiroideo
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
De
Revista:
Praxis (Bern 1994)
Asunto de la revista:
MEDICINA
Año:
2019
Tipo del documento:
Article