ACTH-producing thymic neuroendocrine tumor initially presenting as psychosis: A case report and literature review.
Thorac Cancer
; 10(7): 1648-1653, 2019 07.
Article
en En
| MEDLINE
| ID: mdl-31187563
ABSTRACT
A 32-year-old woman was referred to our hospital because of severe psychosis and was found to have an ectopic ACTH-producing thymic neuroendocrine tumor. Laboratory data revealed an elevated serum cortisol and plasma ACTH level, hypokalemia, and metabolic alkalosis. Chest computed tomography (CT) revealed an anterior mediastinal mass and multiple pulmonary nodules. As the patient was unable to communicate because of her consciousness disturbance, she was managed with artificial ventilation and deep sedation. Metyrapone and potassium supplementation were administered, and steroid psychosis gradually improved. Thoracic surgery was performed and the histopathological diagnosis was thymic neuroendocrine tumor with positive anti-ACTH immunohistochemical staining. Here we present details of the case and review the literature.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trastornos Psicóticos
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Neoplasias del Timo
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Tumores Neuroendocrinos
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Hormona Adrenocorticotrópica
Límite:
Adult
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Female
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Humans
Idioma:
En
Revista:
Thorac Cancer
Año:
2019
Tipo del documento:
Article
País de afiliación:
Japón