Translatable gene therapy for lung cancer using Crispr CAS9-an exploratory review.
Cancer Gene Ther
; 27(3-4): 116-124, 2020 04.
Article
en En
| MEDLINE
| ID: mdl-31222183
ABSTRACT
Gene therapy using CRISPR Cas9 technique is rapidly gaining popularity among the scientific community primarily because of its versatility, cost-effectiveness, and high efficacy. While the laboratory-based experiments and findings making use of CRISPR as a gene editing tool are available in ample amounts, the question arises that how much of these findings are actually translatable into measures helping in combating particular disease conditions. In this review, we highlight the important studies and findings done till now in the perspective of lung cancer with an in-depth analysis of various clinical trials associated with the use of CRISPR Cas9 technology in the field of cancer research.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Terapia Genética
/
Carcinoma de Pulmón de Células no Pequeñas
/
Investigación Biomédica Traslacional
/
Sistemas CRISPR-Cas
/
Neoplasias Pulmonares
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Cancer Gene Ther
Asunto de la revista:
GENETICA MEDICA
/
NEOPLASIAS
/
TERAPEUTICA
Año:
2020
Tipo del documento:
Article
País de afiliación:
India