C8-Substituted Imidazotetrazine Analogs Overcome Temozolomide Resistance by Inducing DNA Adducts and DNA Damage.

Yang, Zhikuan; Wei, Danping; Dai, Xiaoli; Stevens, Malcolm F G; Bradshaw, Tracey D; Luo, Ying; Zhang, Jihong

Yang, Zhikuan; Wei, Danping; Dai, Xiaoli; Stevens, Malcolm F G; Bradshaw, Tracey D; Luo, Ying; Zhang, Jihong.

Afiliación

Yang Z; Medical School, Kunming University of Science and Technology, Kunming, China.
Wei D; Medical School, Kunming University of Science and Technology, Kunming, China.
Dai X; Medical School, Kunming University of Science and Technology, Kunming, China.
Stevens MFG; Centre for Biomolecular Sciences, University of Nottingham, Nottingham, United Kingdom.
Bradshaw TD; Centre for Biomolecular Sciences, University of Nottingham, Nottingham, United Kingdom.
Luo Y; Medical School, Kunming University of Science and Technology, Kunming, China.
Zhang J; Medical School, Kunming University of Science and Technology, Kunming, China.

Front Oncol ; 9: 485, 2019.

Article en En | MEDLINE | ID: mdl-31263673

Palabras clave

DNA adducts; O6-methylguanine-DNA methyltransferase; apoptosis; colorectal carcinoma; glioblastoma

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Oncol Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza

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