A nanocomposite consisting of MnO2 nanoflowers and the conducting polymer PEDOT for highly sensitive amperometric detection of paracetamol.
Mikrochim Acta
; 186(8): 499, 2019 07 03.
Article
en En
| MEDLINE
| ID: mdl-31270688
ABSTRACT
An electrochemical sensor for paracetamol is described that consists of a glassy carbon electrode (GCE) that was modified with the conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT) doped with MnO2 nanoflowers. The hydrothermally synthesized MnO2 nanoflowers possess a large surface area and can be doped into PEDOT through electrochemical deposition to form a conducting polymer nanocomposite. The nanoflowers are shown to be uniformly distributed within the nanocomposite as revealed by elemental mapping analysis. The nanocomposite displays excellent catalytic activity toward the electrochemical oxidation of paracetamol. The modified GCE, best operated at a working potential of around 0.37 V (vs. SCE) has a linear response in 0.06 to 435 µM paracetamol concentration range and a very low limit of detection (31 nM at a signal-to-noise ratio of 3). The sensor exhibits excellent reproducibility and stability, and satisfying accuracy for paracetamol detection in pharmaceutical samples. Graphical abstract A highly sensitive electrochemical sensor capable of detecting paracetamol with a limit of detection down to 31 nM was developed based on MnO2 nanoflowers doped conducting polymer PEDOT.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Óxidos
/
Polímeros
/
Compuestos de Manganeso
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Compuestos Bicíclicos Heterocíclicos con Puentes
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Nanocompuestos
/
Analgésicos
/
Acetaminofén
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
Mikrochim Acta
Año:
2019
Tipo del documento:
Article
País de afiliación:
China