Association Between Neonatal Thyroid Stimulating Hormone Status and Maternal Urinary Iodine Status.
Indian Pediatr
; 56(6): 472-475, 2019 06 15.
Article
en En
| MEDLINE
| ID: mdl-31278226
ABSTRACT
BACKGROUND:
Maternal urinary iodine concentration (MUIC) and percentage of neonates with Thyroid stimulating hormone (TSH) >5 mIU/L are amongst the parameters suggested for assessing adequate iodine status.OBJECTIVE:
To assess the correlation between MUIC and neonatal TSH levels. STUDYDESIGN:
Cross-sectional. SETTINGS Tertiary care center in Delhi, India, between November 2015 to November 2016.PARTICIPANTS:
Postnatal mother-neonate dyads.METHODS:
TSH levels assessed among neonatal samples were stratified as below and above 5 mIU/L. MUIC was measured in 544 mothers, 400 mother-neonate dyads with neonatal TSH levels >5 mIU/L (cases) and 144 mother-neonate newborn mother dyads with neonatal TSH <5 mIU/L (controls).RESULTS:
Results:
The percentage of mothers with iodine insufficiency (9.8% vs 5.6%) as well as iodine excess (54.3% vs 41.7%) were significant higher in cases than controls. Mean TSH was also higher (P=0.0002) in both the iodine deficient and iodine excess group. There was no correlation between neonatal TSH values and MUIC.CONCLUSION:
Lack of correlation between neonatal TSH and MUIC is due to iodine excess together with iodine deficiency.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades de la Tiroides
/
Tirotropina
/
Tamizaje Neonatal
/
Yodo
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adult
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Female
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Humans
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Male
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Newborn
Idioma:
En
Revista:
Indian Pediatr
Año:
2019
Tipo del documento:
Article
País de afiliación:
India