Preliminary assessment of anti-α-Gal IgG and IgM levels in patients with patent Plasmodium vivax infection.
Mem Inst Oswaldo Cruz
; 114: e190145, 2019.
Article
en En
| MEDLINE
| ID: mdl-31291383
ABSTRACT
Anti-α-Gal responses may exert a protective effect in falciparum malaria. However, the biological role of such antibodies is still unknown during Plasmodium vivax infections. We investigated IgG and IgM responses to α-Gal in individuals with vivax malaria. Anti-α-Gal IgG and IgM levels were higher in these patients than in controls, but no significant correlation was found between parasitaemia and anti-α-Gal response, nor between this response and ABO blood group status. This is the first study to investigate anti-α-Gal antibodies in P. vivax-infected patients; a larger survey is necessary to achieve a better understanding of host immune response during vivax malaria.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plasmodium vivax
/
Inmunoglobulina G
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Inmunoglobulina M
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Anticuerpos Antiidiotipos
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Malaria Vivax
Límite:
Adult
/
Humans
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Middle aged
Idioma:
En
Revista:
Mem Inst Oswaldo Cruz
Año:
2019
Tipo del documento:
Article
País de afiliación:
Brasil