Targeting microRNA-134 for seizure control and disease modification in epilepsy.

Morris, Gareth; Reschke, Cristina R; Henshall, David C

Morris, Gareth; Reschke, Cristina R; Henshall, David C.

Afiliación

Morris G; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland; FutureNeuro Research Centre, Royal College of Surgeons in Ireland, Dublin, Ireland.
Reschke CR; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland; FutureNeuro Research Centre, Royal College of Surgeons in Ireland, Dublin, Ireland.
Henshall DC; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland; FutureNeuro Research Centre, Royal College of Surgeons in Ireland, Dublin, Ireland. Electronic address: dhenshall@rcsi.ie.

EBioMedicine ; 45: 646-654, 2019 Jul.

Article en En | MEDLINE | ID: mdl-31300345

Asunto(s)

Epilepsia/terapia; MicroARNs/genética; Neuronas/metabolismo; Convulsiones/terapia; Animales; Encéfalo/metabolismo; Encéfalo/patología; Modelos Animales de Enfermedad; Epilepsia/genética; Epilepsia/patología; Hipocampo/metabolismo; Hipocampo/patología; Humanos; MicroARNs/antagonistas & inhibidores; MicroARNs/uso terapéutico; Neuronas/patología; Oligonucleótidos Antisentido/genética; Oligonucleótidos Antisentido/uso terapéutico; Convulsiones/genética

Palabras clave

Biomarker; Epileptogenesis; Hippocampal sclerosis; Noncoding RNA; RNA therapy

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Convulsiones / MicroARNs / Epilepsia / Neuronas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: EBioMedicine Año: 2019 Tipo del documento: Article País de afiliación: Irlanda Pais de publicación: Países Bajos

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