Genetic characterization of Echinococcus species in eastern Ethiopia.
Vet Parasitol Reg Stud Reports
; 17: 100302, 2019 08.
Article
en En
| MEDLINE
| ID: mdl-31303217
ABSTRACT
Cystic echinococcosis (CE) is a neglected zoonotic disease with considerable economic and public health burden worldwide, particularly affecting developing countries like Ethiopia. To initiate effective prevention and control of CE, comprehensive data on the local lifecycles of the various species/genotypes of Echinococcus are needed. In the present study, conducted in eastern Ethiopia, a total of 1106 livestock animals were examined at three slaughterhouses, which resulted in combined prevalence of morphologically and molecularly confirmed CE of 8.4% (75/891) in cattle, 1.1% (1/95) in sheep, 0.0% (0/95) in goats and 12.0% (3/25) in camels. All cystic lesions recovered during post mortem examination were assessed for cyst condition and underwent molecular characterization by PCR and sequencing of a 1081â¯bp fragment of the mitochondrial cox1 gene. A total of 175 cysts belonged to E. granulosus s.s. (nâ¯=â¯165), E. ortleppi (nâ¯=â¯6) and E. canadensis G6/7 (nâ¯=â¯4). Of all examined cysts, only 14 were fertile and contained protoscoleces, all from the lungs of cattle 5 were E. granulosus s.s., 6 E. ortleppi and 3 E. canadensis G6/7. In sheep, only one sterile liver cyst of E. granulosus s.s. was found, while in camels seven sterile or caseated/calcified cysts of E. granulosus s.s. and E. canadensis G6/7 were found in liver and lungs. In conclusion, the prevalence of CE was rather low compared to other regions of Ethiopia, and, based on the number of fertile cysts, three Echinococcus spp. contributed almost equally to transmission. Cattle seem to be, epidemiologically, the most important livestock species. Our data provide a substantial basis for more detailed investigations of the transmission dynamics of CE in the study area.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Equinococosis
/
Echinococcus
/
Ganado
Tipo de estudio:
Prevalence_studies
/
Risk_factors_studies
Límite:
Animals
País/Región como asunto:
Africa
Idioma:
En
Revista:
Vet Parasitol Reg Stud Reports
Año:
2019
Tipo del documento:
Article
País de afiliación:
Etiopia
Pais de publicación:
HOLANDA
/
HOLLAND
/
NETHERLANDS
/
NL
/
PAISES BAJOS
/
THE NETHERLANDS