Effects of D-5-hydroxytryptophan and D-DOPA on binding at serotonin and dopamine receptors.
Res Commun Chem Pathol Pharmacol
; 60(1): 129-32, 1988 Apr.
Article
en En
| MEDLINE
| ID: mdl-3132733
ABSTRACT
Binding of the D-amino acids D-5-hydroxytryptophan (D-5-HTP) and D-dihydroxyphenylalanine (D-DOPA) to high affinity sites for serotonin (5-HT) and dopamine (DA) was studied in bovine striatum. D-5-HT bound to the 5-HT site with affinity in the micromolar range, but showed no appreciable binding at the DA site. D-DOPA showed little binding to either 5-HT or DA receptors.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Dihidroxifenilalanina
/
5-Hidroxitriptófano
/
Receptores de Serotonina
/
Receptores Dopaminérgicos
Límite:
Animals
Idioma:
En
Revista:
Res Commun Chem Pathol Pharmacol
Año:
1988
Tipo del documento:
Article