[Minimal change disease during lithium therapy: case report].
G Ital Nefrol
; 36(4)2019 Jul 24.
Article
en It
| MEDLINE
| ID: mdl-31373471
ABSTRACT
Lithium is a largely used and effective therapy in the treatment of bipolar disorder. Its toxic effects on kidneys are mostly diabetes insipidus, hyperchloremic metabolic acidosis and tubulointerstitial nephritis. Also, a correlation between lithium and minimal change disease has sometimes been described. We report here the case of a patient with severe bipolar disorder on lithium therapy who, without any pre-existing nephropathy, developed nephrotic syndrome and AKI with histopathologic findings pointing to minimal change disease. The patient was treated with symptomatic therapy; the discontinuation of lithium therapy resulted in the remission of AKI and of the nephrotic syndrome, thus suggesting a close relationship between lithium and minimal change disease.
Palabras clave
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trastorno Bipolar
/
Compuestos de Litio
/
Antimaníacos
/
Nefrosis Lipoidea
/
Síndrome Nefrótico
Límite:
Humans
/
Male
/
Middle aged
Idioma:
It
Revista:
G Ital Nefrol
Asunto de la revista:
NEFROLOGIA
Año:
2019
Tipo del documento:
Article
Pais de publicación:
IT
/
ITALIA
/
ITALY
/
ITÁLIA