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An investigation of targeted inhibition of transcription factor activity with pyrrole imidazole polyamide (PA) in chronic myeloid leukemia (CML) blast crisis cells.
Hayatigolkhatmi, K; Padroni, G; Su, W; Fang, L; Gómez-Castañeda, E; Hsieh, Y C; Jackson, L; Pellicano, F; Burley, G A; Jørgensen, H G.
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  • Hayatigolkhatmi K; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, UK.
  • Padroni G; Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, Glasgow, UK.
  • Su W; Guangdong Key Laboratory of Nanomedicine, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, PR China.
  • Fang L; Guangdong Key Laboratory of Nanomedicine, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, PR China.
  • Gómez-Castañeda E; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, UK.
  • Hsieh YC; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, UK.
  • Jackson L; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, UK.
  • Pellicano F; Drug Discovery Program, Cancer Research UK Beatson Institute, Garscube Estate, Glasgow, UK.
  • Burley GA; Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, Glasgow, UK.
  • Jørgensen HG; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, UK. Electronic address: heather.jorgensen@glasgow.ac.uk.
Bioorg Med Chem Lett ; 29(18): 2622-2625, 2019 09 15.
Article en En | MEDLINE | ID: mdl-31378570
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirroles / Leucemia Mielógena Crónica BCR-ABL Positiva / Crisis Blástica / Inhibidores de Proteínas Quinasas / Imidazoles / Antineoplásicos / Nylons Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirroles / Leucemia Mielógena Crónica BCR-ABL Positiva / Crisis Blástica / Inhibidores de Proteínas Quinasas / Imidazoles / Antineoplásicos / Nylons Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido