Serum endocan levels, carotid intima-media thickness and microalbuminuria in patients with newly diagnosed hypertension.
Clin Exp Hypertens
; 41(8): 787-794, 2019.
Article
en En
| MEDLINE
| ID: mdl-31390906
ABSTRACT
Background:
Endocan is a particular protein of endothelial cells. The purpose of this study was to determine the relationship of serum endocan levels with carotid intima-media thickness (cIMT), inflammation, and microalbuminuria in patients with newly-diagnosed hypertension.Materials-Methods:
This prospective study included 61 patients with newly-diagnosed hypertension (HT) and 30 controls. Endocan, microalbuminuria and cIMT measurements were taken from all patients.Results:
The serum endocan levels, the mean cIMT and microalbuminuria levels of patients with HT were significantly higher than those of the control group (p < .0001, p = .015 and p < .001, respectively).Conclusion:
We found that endocan levels were increased in our study. This increase in endocan levels shows a relation with cIMT and microalbuminuria, which are associated with endothelial dysfunction.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteoglicanos
/
Arterias Carótidas
/
Albuminuria
/
Grosor Intima-Media Carotídeo
/
Hipertensión
/
Proteínas de Neoplasias
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Clin Exp Hypertens
Año:
2019
Tipo del documento:
Article
País de afiliación:
Turquía