Antibacterial activity of new structural class of semisynthetic molecule, triphenyl-phosphonium conjugated diarylheptanoid.

Kumari, Shweta; Jayakumar, Sundarraj; Gupta, Gagan D; Bihani, Subhash C; Sharma, Deepak; Kutala, Vijay K; Sandur, Santosh K; Kumar, Vinay

Kumari, Shweta; Jayakumar, Sundarraj; Gupta, Gagan D; Bihani, Subhash C; Sharma, Deepak; Kutala, Vijay K; Sandur, Santosh K; Kumar, Vinay.

Afiliación

Kumari S; Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, 400085, India.
Jayakumar S; Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, 400085, India.
Gupta GD; Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, 400085, India; Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, Maharashtra, 400094, India.
Bihani SC; Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, 400085, India.
Sharma D; Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, 400085, India; Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, Maharashtra, 400094, India.
Kutala VK; Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Sandur SK; Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, 400085, India; Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, Maharashtra, 400094, India. Electronic address: sskumar@barc.gov.in.
Kumar V; Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, 400085, India; Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, Maharashtra, 400094, India. Electronic address: vinay@barc.gov.in.

Free Radic Biol Med ; 143: 140-145, 2019 11 01.

Article en En | MEDLINE | ID: mdl-31398499

Asunto(s)

Antibacterianos/farmacología; Curcumina/análogos & derivados; Curcumina/farmacología; Diarilheptanoides/farmacología; Animales; Antioxidantes/farmacología; Bacillus subtilis/efectos de los fármacos; Muerte Celular; Línea Celular; Cromanos/farmacología; Farmacorresistencia Bacteriana; Escherichia coli/efectos de los fármacos; Voluntarios Sanos; Humanos; Leucocitos/efectos de los fármacos; Leucocitos Mononucleares/efectos de los fármacos; Pulmón/efectos de los fármacos; Potenciales de la Membrana; Ratones; Pruebas de Sensibilidad Microbiana; Microscopía Electrónica de Rastreo; Mycobacterium smegmatis/efectos de los fármacos; Especies Reactivas de Oxígeno

Palabras clave

Antimicrobial susceptibility; Membrane potential; Minimal inhibitory concentration (MIC); Mitocurcumin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Curcumina / Diarilheptanoides / Antibacterianos Límite: Animals / Humans Idioma: En Revista: Free Radic Biol Med Asunto de la revista: BIOQUIMICA / MEDICINA Año: 2019 Tipo del documento: Article País de afiliación: India Pais de publicación: Estados Unidos

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