Towards clinical grating-interferometry mammography.
Eur Radiol
; 30(3): 1419-1425, 2020 Mar.
Article
en En
| MEDLINE
| ID: mdl-31440834
ABSTRACT
OBJECTIVES:
Grating-interferometry-based mammography (GIM) might facilitate breast cancer detection, as several research works have demonstrated in a pre-clinical setting, since it is able to provide attenuation, differential phase contrast, and scattering images simultaneously. In order to translate this technique to the clinics, it has to be adapted to cover a large field-of-view within a clinically acceptable exposure time and radiation dose.METHODS:
We set up a grating interferometer that fits into a standard mammography system and fulfilled the aforementioned conditions. Here, we present the first mastectomy images acquired with this experimental device. RESULTS ANDCONCLUSION:
Our system performs at a mean glandular dose of 1.6 mGy for a 5-cm-thick, 18%-dense breast, and a field-of-view of 26 × 21 cm2. It seems to be well-suited as basis for a clinical-environment device. Further, dark-field signals seem to support an improved lesion visualization. Evidently, the effective impact of such indications must be evaluated and quantified within the context of a proper reader study. KEY POINTS ⢠Grating-interferometry-based mammography (GIM) might facilitate breast cancer detection, since it is sensitive to refraction and scattering and thus provides additional tissue information. ⢠The most straightforward way to do grating-interferometry in the clinics is to modify a standard mammography device. ⢠In a first approximation, the doses given with this technique seem to be similar to those of conventional mammography.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias de la Mama
/
Mamografía
/
Carcinoma Ductal de Mama
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Carcinoma Intraductal no Infiltrante
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Neoplasias Primarias Múltiples
Límite:
Female
/
Humans
Idioma:
En
Revista:
Eur Radiol
Asunto de la revista:
RADIOLOGIA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Suiza
Pais de publicación:
ALEMANHA
/
ALEMANIA
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DE
/
DEUSTCHLAND
/
GERMANY