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A New Lead Identification Strategy: Screening an sp3 -rich and Lead-like Compound Library Composed of 7-Azanorbornane Derivatives.
Karaki, Fumika; Umemoto, Sho; Ashizawa, Karin; Oki, Tomoya; Sato, Noriko; Ogino, Takumi; Ishibashi, Naoto; Someya, Ryoto; Miyano, Kanako; Hirayama, Shigeto; Uezono, Yasuhito; Fujii, Hideaki.
Afiliación
  • Karaki F; Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Umemoto S; Medicinal Research Laboratories, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Ashizawa K; Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Oki T; Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Sato N; Division of Cancer Pathophysiology, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
  • Ogino T; Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Ishibashi N; Analytical Unit for Organic Chemistry, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Someya R; Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Miyano K; Division of Cancer Pathophysiology, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
  • Hirayama S; Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Uezono Y; Division of Cancer Pathophysiology, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
  • Fujii H; Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
ChemMedChem ; 14(21): 1840-1848, 2019 11 06.
Article en En | MEDLINE | ID: mdl-31444850
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos Aza / Bibliotecas de Moléculas Pequeñas / Norbornanos Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: ChemMedChem Asunto de la revista: FARMACOLOGIA / QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Japón
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos Aza / Bibliotecas de Moléculas Pequeñas / Norbornanos Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: ChemMedChem Asunto de la revista: FARMACOLOGIA / QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Japón