Perinatal carotid artery ischemic stroke: Report of two cases.
J Neonatal Perinatal Med
; 12(4): 479-485, 2019.
Article
en En
| MEDLINE
| ID: mdl-31450516
ABSTRACT
The mechanisms of perinatal stroke are poorly understood but preclinical studies point to the crucial role of perinatal inflammation. Carotid artery occlusion represents a very rare and severe cause of perinatal stroke. We describe two cases diagnosed with extensive ischemic stroke due to carotid artery occlusion. In both cases, we demonstrated placental vasculopathy. High levels of C-reactive protein in mother and/or neonates suggested inflammatory mechanism as a potential trigger. Both cases underwent hypothermic treatment without complications because of initial diagnosis of perinatal asphyxia. The prognosis at the time of the last follow up was severe including cerebral palsy, epilepsy and cognitive impairment. Our cases contribute to the actual debate on pathogenic mechanisms and treatment options for this rare condition.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Arterias Carótidas
/
Infarto Cerebral
/
Isquemia Encefálica
/
Parálisis Cerebral
/
Trastornos del Neurodesarrollo
/
Enfermedades del Prematuro
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Child, preschool
/
Female
/
Humans
/
Newborn
Idioma:
En
Revista:
J Neonatal Perinatal Med
Año:
2019
Tipo del documento:
Article
País de afiliación:
Italia