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Survey of the erythrocyte EPA+DHA levels in the heart attack/stroke belt.
Harris, W S; Jackson, K H; Brenna, J T; Rodriguez, J C; Tintle, N L; Cornish, L.
Afiliación
  • Harris WS; OmegaQuant Analytics, LLC, Sioux Falls, SD, USA; Sanford School of Medicine, University of South Dakota, Sioux Falls, SD, USA. Electronic address: bill@omegaquant.com.
  • Jackson KH; OmegaQuant Analytics, LLC, Sioux Falls, SD, USA.
  • Brenna JT; Dell Medical School, University of Texas at Austin, Austin, TX, USA.
  • Rodriguez JC; Brooks College of Health, University of North Florida, Jacksonville, FL, USA.
  • Tintle NL; Dordt College, Sioux Center, IA, USA.
  • Cornish L; Seafood Nutrition Partnership, Washington, DC, USA.
Article en En | MEDLINE | ID: mdl-31492431
BACKGROUND: The Omega-3 Index (O3I; erythrocyte EPA+DHA as a percent of total fatty acids) is inversely related to risk for cardiovascular disease (CVD). The cardioprotective target O3I is 8%-12%. O3I levels in American regions with high CVD risk are poorly characterized. PURPOSE: To determine the O3I in individuals participating in a Seafood Nutrition Partnership (SNP) survey in seven US cities in the CVD "belt." METHODS: Fingerstick blood samples were analyzed for the O3I. RESULTS: The SNP cohort (n = 2177) had a mean (SD) O3I of 4.42% (1.12%). Only 1.2% were in the desirable range, whereas 42% had an undesirable (<4%) O3I. The mean (SD) O3I in a subset of 772 SNP subjects who were matched for age and sex with the Framingham study was 4.6% (1.2%) compared 5.3% (1.6%) in the Framingham cohort (p < 0.0001). CONCLUSIONS: Individuals in the CVD "belt" had relatively low O3I levels. Since in other settings, a low O3I is associated with increased risk for CVD, this may be one factor contributing to the higher risk for CVD in this region of the US.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Eicosapentaenoico / Ácidos Docosahexaenoicos / Accidente Cerebrovascular / Eritrocitos / Infarto del Miocardio Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male País/Región como asunto: America do norte Idioma: En Revista: Prostaglandins Leukot Essent Fatty Acids Asunto de la revista: ENDOCRINOLOGIA Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Eicosapentaenoico / Ácidos Docosahexaenoicos / Accidente Cerebrovascular / Eritrocitos / Infarto del Miocardio Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male País/Región como asunto: America do norte Idioma: En Revista: Prostaglandins Leukot Essent Fatty Acids Asunto de la revista: ENDOCRINOLOGIA Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido