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A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model.
Yant, Stephen R; Mulato, Andrew; Hansen, Derek; Tse, Winston C; Niedziela-Majka, Anita; Zhang, Jennifer R; Stepan, George J; Jin, Debi; Wong, Melanie H; Perreira, Jill M; Singer, Eric; Papalia, Giuseppe A; Hu, Eric Y; Zheng, Jim; Lu, Bing; Schroeder, Scott D; Chou, Kevin; Ahmadyar, Shekeba; Liclican, Albert; Yu, Helen; Novikov, Nikolai; Paoli, Eric; Gonik, Daniel; Ram, Renee R; Hung, Magdeleine; McDougall, William M; Brass, Abraham L; Sundquist, Wesley I; Cihlar, Tomas; Link, John O.
Afiliación
  • Yant SR; Gilead Sciences, Foster City, CA, USA. stephen.yant@gilead.com.
  • Mulato A; Gilead Sciences, Foster City, CA, USA.
  • Hansen D; Gilead Sciences, Foster City, CA, USA.
  • Tse WC; Gilead Sciences, Foster City, CA, USA.
  • Niedziela-Majka A; Vir Biotechnology, Inc., San Francisco, CA, USA.
  • Zhang JR; Gilead Sciences, Foster City, CA, USA.
  • Stepan GJ; Gilead Sciences, Foster City, CA, USA.
  • Jin D; Gilead Sciences, Foster City, CA, USA.
  • Wong MH; Gilead Sciences, Foster City, CA, USA.
  • Perreira JM; Gilead Sciences, Foster City, CA, USA.
  • Singer E; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA, USA.
  • Papalia GA; Gilead Sciences, Foster City, CA, USA.
  • Hu EY; Gilead Sciences, Foster City, CA, USA.
  • Zheng J; Gilead Sciences, Foster City, CA, USA.
  • Lu B; Gilead Sciences, Foster City, CA, USA.
  • Schroeder SD; Gilead Sciences, Foster City, CA, USA.
  • Chou K; Gilead Sciences, Foster City, CA, USA.
  • Ahmadyar S; Gilead Sciences, Foster City, CA, USA.
  • Liclican A; Gilead Sciences, Foster City, CA, USA.
  • Yu H; Gilead Sciences, Foster City, CA, USA.
  • Novikov N; Gilead Sciences, Foster City, CA, USA.
  • Paoli E; Gilead Sciences, Foster City, CA, USA.
  • Gonik D; Gilead Sciences, Foster City, CA, USA.
  • Ram RR; Gilead Sciences, Foster City, CA, USA.
  • Hung M; Gilead Sciences, Foster City, CA, USA.
  • McDougall WM; Gilead Sciences, Foster City, CA, USA.
  • Brass AL; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA, USA.
  • Sundquist WI; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA, USA.
  • Cihlar T; Gastroenterology Division, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
  • Link JO; Peak Gastroenterology Associates, Colorado Springs, CO, USA.
Nat Med ; 25(9): 1377-1384, 2019 09.
Article en En | MEDLINE | ID: mdl-31501601
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridinas / Infecciones por VIH / VIH-1 / Fármacos Anti-VIH / Proteínas de la Cápside / Bibliotecas de Moléculas Pequeñas / Indazoles Límite: Animals / Humans Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridinas / Infecciones por VIH / VIH-1 / Fármacos Anti-VIH / Proteínas de la Cápside / Bibliotecas de Moléculas Pequeñas / Indazoles Límite: Animals / Humans Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos