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A Rare Mutation in SMAD9 Associated With High Bone Mass Identifies the SMAD-Dependent BMP Signaling Pathway as a Potential Anabolic Target for Osteoporosis.
Gregson, Celia L; Bergen, Dylan J M; Leo, Paul; Sessions, Richard B; Wheeler, Lawrie; Hartley, April; Youlten, Scott; Croucher, Peter I; McInerney-Leo, Aideen M; Fraser, William; Tang, Jonathan Cy; Anderson, Lisa; Marshall, Mhairi; Sergot, Leon; Paternoster, Lavinia; Davey Smith, George; Brown, Matthew A; Hammond, Chrissy; Kemp, John P; Tobias, Jon H; Duncan, Emma L.
Afiliación
  • Gregson CL; Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Bergen DJM; Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Leo P; School of Physiology, Pharmacology, and Neuroscience, Faculty of Life Sciences, University of Bristol, Bristol, UK.
  • Sessions RB; Faculty of Health, Translational Genomics Group, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Translational Research Institute, Princess Alexandra Hospital, Woolloongabba, Australia.
  • Wheeler L; Faculty of Life Sciences, School of Biochemistry, University of Bristol, Bristol, UK.
  • Hartley A; Faculty of Health, Translational Genomics Group, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Translational Research Institute, Princess Alexandra Hospital, Woolloongabba, Australia.
  • Youlten S; Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Croucher PI; Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • McInerney-Leo AM; Division of Bone Biology, Garvan Institute of Medical Research, Sydney, Australia.
  • Fraser W; Division of Bone Biology, Garvan Institute of Medical Research, Sydney, Australia.
  • Tang JC; Faculty of Medicine, St Vincent's Clinical School, UNSW Sydney, Sydney, Australia.
  • Anderson L; School of Biotechnology and Biomolecular Sciences, UNSW Sydney, Sydney, Australia.
  • Marshall M; Faculty of Health, Translational Genomics Group, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Translational Research Institute, Princess Alexandra Hospital, Woolloongabba, Australia.
  • Sergot L; Dermatology Research Centre, The University of Queensland, The University of Queensland Diamantina Institute, Brisbane, Australia.
  • Paternoster L; Norwich Medical School, University of East Anglia, Norwich, UK.
  • Davey Smith G; Department of Diabetes, Endocrinology and Clinical Biochemistry, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, UK.
  • Brown MA; Faculty of Health, Translational Genomics Group, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Translational Research Institute, Princess Alexandra Hospital, Woolloongabba, Australia.
  • Hammond C; Faculty of Health, Translational Genomics Group, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Translational Research Institute, Princess Alexandra Hospital, Woolloongabba, Australia.
  • Kemp JP; Severn School of Radiology, Severn Deanery, Bristol, UK.
  • Tobias JH; Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Duncan EL; Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
J Bone Miner Res ; 35(1): 92-105, 2020 01.
Article en En | MEDLINE | ID: mdl-31525280
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoporosis / Pez Cebra Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: J Bone Miner Res Asunto de la revista: METABOLISMO / ORTOPEDIA Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoporosis / Pez Cebra Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: J Bone Miner Res Asunto de la revista: METABOLISMO / ORTOPEDIA Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos