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WZ3146 inhibits mast cell Lyn and Fyn to reduce IgE-mediated allergic responses in vitro and in vivo.
Park, Young Hwan; Kim, Do Kyun; Kim, Hyuk Soon; Lee, Dajeong; Lee, Min Bum; Min, Keun Young; Jo, Min Geun; Lee, Ji Eon; Kim, Young Mi; Choi, Wahn Soo.
Afiliación
  • Park YH; Department of Immunology, College of Medicine, Konkuk University, Chungju 27478, Republic of Korea.
  • Kim DK; Department of Immunology, College of Medicine, Konkuk University, Chungju 27478, Republic of Korea.
  • Kim HS; Department of Immunology, College of Medicine, Konkuk University, Chungju 27478, Republic of Korea.
  • Lee D; Department of Immunology, College of Medicine, Konkuk University, Chungju 27478, Republic of Korea.
  • Lee MB; Department of Immunology, College of Medicine, Konkuk University, Chungju 27478, Republic of Korea.
  • Min KY; Department of Immunology, College of Medicine, Konkuk University, Chungju 27478, Republic of Korea.
  • Jo MG; Department of Immunology, College of Medicine, Konkuk University, Chungju 27478, Republic of Korea.
  • Lee JE; Department of Immunology, College of Medicine, Konkuk University, Chungju 27478, Republic of Korea.
  • Kim YM; College of Pharmacy, Duksung Women's University, Seoul 01369, Republic of Korea.
  • Choi WS; Department of Immunology, College of Medicine, Konkuk University, Chungju 27478, Republic of Korea. Electronic address: wahnchoi@kku.ac.kr.
Toxicol Appl Pharmacol ; 383: 114763, 2019 11 15.
Article en En | MEDLINE | ID: mdl-31526816
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirimidinas / Inmunoglobulina E / Familia-src Quinasas / Proteínas Proto-Oncogénicas c-fyn / Hipersensibilidad / Mastocitos Límite: Animals / Humans / Male Idioma: En Revista: Toxicol Appl Pharmacol Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirimidinas / Inmunoglobulina E / Familia-src Quinasas / Proteínas Proto-Oncogénicas c-fyn / Hipersensibilidad / Mastocitos Límite: Animals / Humans / Male Idioma: En Revista: Toxicol Appl Pharmacol Año: 2019 Tipo del documento: Article