In-Depth Comparison of Lysine-Based Antibody-Drug Conjugates Prepared on Solid Support Versus in Solution.

Arlotta, Keith J; Gandhi, Aditya V; Chen, Hsiao-Nung; Nervig, Christine S; Carpenter, John F; Owen, Shawn C

Arlotta, Keith J; Gandhi, Aditya V; Chen, Hsiao-Nung; Nervig, Christine S; Carpenter, John F; Owen, Shawn C.

Afiliación

Arlotta KJ; Department of Bioengineering, University of Utah, Salt Lake City, UT 84112, USA. keith.arlotta@utah.edu.
Gandhi AV; Department of Pharmaceutical Sciences, Anschutz Medical Campus, University of Colorado, Aurora, CO 80045, USA. ADITYA.GANDHI@ucdenver.edu.
Chen HN; Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT 84112, USA. hsiao.chen@utah.edu.
Nervig CS; Department of Medicinal Chemistry, University of Utah, Salt Lake City, UT 84112, USA. christine.nervig@utah.edu.
Carpenter JF; Department of Pharmaceutical Sciences, Anschutz Medical Campus, University of Colorado, Aurora, CO 80045, USA. John.Carpenter@ucdenver.edu.
Owen SC; Department of Bioengineering, University of Utah, Salt Lake City, UT 84112, USA. Shawn.Owen@hsc.utah.edu.

Antibodies (Basel) ; 7(1)2018 Jan 07.

Article en En | MEDLINE | ID: mdl-31544859

Palabras clave

DLS; DM1; DSC; ITC; LC/MS; Raman; antibody drug conjugates; one-step; protein A; trastuzumab

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Antibodies (Basel) Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

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