Spider Chitin. The biomimetic potential and applications of Caribena versicolor tubular chitin.
Carbohydr Polym
; 226: 115301, 2019 Dec 15.
Article
en En
| MEDLINE
| ID: mdl-31582063
ABSTRACT
Diverse fields of modern technology and biomedicine can benefit from the application of ready-to-use chitin-based scaffolds. In this work we show for the first time the applicability of tubular and porous chitin from Caribena versicolor spiders as a scaffold for the development of an effective CuO/Cu(OH)2 catalyst for the reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AM), and as a scaffold for the tissue engineering of selected cells. The formation of CuO/Cu(OH)2 phases on and within the chitinous tubes leads to a hybrid material with excellent catalytic performance with respect to the reduction of p-nitrophenol. On the other hand, experimental results provide for the first time strong evidence for the biocompatibility of spider chitin with different cell types, a human progenitor cell line (hPheo1), as well as cardiomyocytes differentiated from induced pluripotent stem cells (iPSC-CMs) that were cultured on a tube-like scaffold.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Arácnidos
/
Quitina
/
Ingeniería de Tejidos
/
Materiales Biomiméticos
/
Andamios del Tejido
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Carbohydr Polym
Año:
2019
Tipo del documento:
Article
País de afiliación:
Polonia