Comparative UHPLC-HRMS Profiling, Toxicological Assessment, and Protection Against H2O2-Induced Genotoxicity of Different Parts of Opuntia ficus indica.

Tsafantakis, Nikolaos; Katsanou, Efrosini S; Kyriakopoulou, Katerina; Psarou, Eirini-Christina; Raptaki, Iliana; Skaltsounis, Alexios L; Audebert, Marc; Machera, Kyriaki A; Fokialakis, Nikolas

Comparative UHPLC-HRMS Profiling, Toxicological Assessment, and Protection Against H₂O₂-Induced Genotoxicity of Different Parts of Opuntia ficus indica.

Tsafantakis, Nikolaos; Katsanou, Efrosini S; Kyriakopoulou, Katerina; Psarou, Eirini-Christina; Raptaki, Iliana; Skaltsounis, Alexios L; Audebert, Marc; Machera, Kyriaki A; Fokialakis, Nikolas.

Afiliación

Tsafantakis N; Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece.
Katsanou ES; Laboratory of Pesticides Toxicology, Department of Pesticides Control & Phytopharmacy, Benaki Phytopathological Institute, Athens, Greece.
Kyriakopoulou K; Laboratory of Pesticides Toxicology, Department of Pesticides Control & Phytopharmacy, Benaki Phytopathological Institute, Athens, Greece.
Psarou EC; Laboratory of Pesticides Toxicology, Department of Pesticides Control & Phytopharmacy, Benaki Phytopathological Institute, Athens, Greece.
Raptaki I; Laboratory of Pesticides Toxicology, Department of Pesticides Control & Phytopharmacy, Benaki Phytopathological Institute, Athens, Greece.
Skaltsounis AL; Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece.
Audebert M; UMR1331 Toxalim, Research Centre in Food Toxicology, INRA, Toulouse, France.
Machera KA; Laboratory of Pesticides Toxicology, Department of Pesticides Control & Phytopharmacy, Benaki Phytopathological Institute, Athens, Greece.
Fokialakis N; Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece.

J Med Food ; 22(12): 1280-1293, 2019 Dec.

Article en En | MEDLINE | ID: mdl-31584314

Asunto(s)

Cromatografía Líquida de Alta Presión; Daño del ADN/efectos de los fármacos; Peróxido de Hidrógeno/efectos adversos; Opuntia/química; Extractos Vegetales/farmacología; Antioxidantes/farmacología; Betaxantinas/análisis; Flavonoides/análisis; Flores/anatomía & histología; Frutas/química; Células HeLa; Células Hep G2; Humanos; Hidroxibenzoatos/análisis; Espectrometría de Masas; Pruebas de Mutagenicidad; Fenoles/análisis; Extractos Vegetales/química; Piridinas/análisis; Quercetina/análisis; Semillas/química

Palabras clave

Opuntia ficus indica; antioxidant activity; genotoxicity; phytochemical analysis; toxicity

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Daño del ADN / Extractos Vegetales / Cromatografía Líquida de Alta Presión / Opuntia / Peróxido de Hidrógeno Límite: Humans Idioma: En Revista: J Med Food Asunto de la revista: CIENCIAS DA NUTRICAO / MEDICINA Año: 2019 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Estados Unidos

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