Isolation of Mayaro Virus from a Venezuelan Patient with Febrile Illness, Arthralgias, and Rash: Further Evidence of Regional Strain Circulation and Possible Long-Term Endemicity.
Am J Trop Med Hyg
; 101(6): 1219-1225, 2019 12.
Article
en En
| MEDLINE
| ID: mdl-31595869
ABSTRACT
Fifty-two febrile patients living in Barquisimeto, Venezuela, were screened for arbovirus infection by virus culture during an outbreak of what was thought to be Zika virus infection. We report identification of Mayaro virus (MAYV) on culture of plasma from one patient, an 18-year-old woman with acute febrile illness, arthralgias, and psoriasiform rash. The strain was sequenced and was found to be most closely related to a 1999 strain from French Guiana, which, in turn, was related to two 2014 strains from Haiti. By contrast, previously reported outbreak-related MAYV strains from a sylvatic area approximately 80 miles from where the case patient lived were most closely related to Peruvian isolates. The two strain groups show evidence of having diverged genetically approximately 100 years ago.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones por Alphavirus
/
Alphavirus
/
Artralgia
/
Exantema
/
Fiebre
Tipo de estudio:
Prognostic_studies
Límite:
Adolescent
/
Female
/
Humans
País/Región como asunto:
America do sul
/
Venezuela
Idioma:
En
Revista:
Am J Trop Med Hyg
Año:
2019
Tipo del documento:
Article
País de afiliación:
Venezuela