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Anticancer auranofin engages 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) as a target.
Tian, Songhai; Siu, Fung-Ming; Lok, Chun-Nam; Fung, Yi Man Eva; Che, Chi-Ming.
Afiliación
  • Tian S; Department of Chemistry, The University of Hong Kong, Chemical Biology Centre, The Hong Kong Jockey Club Building for Interdisciplinary Research, Sassoon Road, Hong Kong SAR, China. eva.fungym@hku.hk.
  • Siu FM; Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China. cmche@hku.hk.
  • Lok CN; Department of Chemistry, The University of Hong Kong, Chemical Biology Centre, The Hong Kong Jockey Club Building for Interdisciplinary Research, Sassoon Road, Hong Kong SAR, China. eva.fungym@hku.hk.
  • Fung YME; Department of Chemistry, The University of Hong Kong, Chemical Biology Centre, The Hong Kong Jockey Club Building for Interdisciplinary Research, Sassoon Road, Hong Kong SAR, China. eva.fungym@hku.hk.
  • Che CM; Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China. cmche@hku.hk.
Metallomics ; 11(11): 1925-1936, 2019 11 01.
Article en En | MEDLINE | ID: mdl-31631207
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Auranofina / Terapia Molecular Dirigida / Hidroximetilglutaril-CoA Reductasas / Antineoplásicos Límite: Humans Idioma: En Revista: Metallomics Asunto de la revista: BIOQUIMICA Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Auranofina / Terapia Molecular Dirigida / Hidroximetilglutaril-CoA Reductasas / Antineoplásicos Límite: Humans Idioma: En Revista: Metallomics Asunto de la revista: BIOQUIMICA Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido