Homology Modeling of P2X Receptors.

Stavrou, Anastasios; Dayl, Sudad; Schmid, Ralf

Stavrou, Anastasios; Dayl, Sudad; Schmid, Ralf.

Afiliación

Stavrou A; Department of Molecular and Cell Biology, University of Leicester, Leicester, UK.
Dayl S; Department of Chemistry, College of Science, University of Baghdad, Baghdad, Iraq.
Schmid R; Department of Molecular and Cell Biology, University of Leicester, Leicester, UK. R.Schmid@le.ac.uk.

Methods Mol Biol ; 2041: 65-75, 2020.

Article en En | MEDLINE | ID: mdl-31646480

ABSTRACT

ABSTRACT

Since the X-ray structure of the zebra fish P2X4 receptor in the closed state was published in 2009 homology modeling has been used to generate structural models for P2X receptors. In this chapter, we outline how to use the MODELLER software to generate such structural models for P2X receptors whose structures have not been solved yet.

Asunto(s)

Receptores Purinérgicos P2X/química; Programas Informáticos; Homología Estructural de Proteína; Secuencia de Aminoácidos; Animales; Humanos; Homología de Secuencia

Palabras clave

Homology modeling; Ion channel; MODELLER software; P2X receptor; Protein structure prediction

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Programas Informáticos / Homología Estructural de Proteína / Receptores Purinérgicos P2X Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido

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