PRRX1-induced epithelial-to-mesenchymal transition in salivary adenoid cystic carcinoma activates the metabolic reprogramming of free fatty acids to promote invasion and metastasis.

Jiang, Ya-Ping; Tang, Ya-Ling; Wang, Sha-Sha; Wu, Jia-Shun; Zhang, Mei; Pang, Xin; Wu, Jing-Biao; Chen, Yu; Tang, Ya-Jie; Liang, Xin-Hua

Jiang, Ya-Ping; Tang, Ya-Ling; Wang, Sha-Sha; Wu, Jia-Shun; Zhang, Mei; Pang, Xin; Wu, Jing-Biao; Chen, Yu; Tang, Ya-Jie; Liang, Xin-Hua.

Afiliación

Jiang YP; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology (Sichuan University), Chengdu, China.
Tang YL; Department of Implant, The Affiliated Hospital of Qingdao University, Qingdao, China.
Wang SS; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology (Sichuan University), Chengdu, China.
Wu JS; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology (Sichuan University), Chengdu, China.
Zhang M; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology (Sichuan University), Chengdu, China.
Pang X; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology (Sichuan University), Chengdu, China.
Wu JB; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology (Sichuan University), Chengdu, China.
Chen Y; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology (Sichuan University), Chengdu, China.
Tang YJ; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology (Sichuan University), Chengdu, China.
Liang XH; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.

Cell Prolif ; 53(1): e12705, 2020 Jan.

Article en En | MEDLINE | ID: mdl-31657086

Asunto(s)

Carcinoma Adenoide Quístico/metabolismo; Reprogramación Celular; Transición Epitelial-Mesenquimal; Ácidos Grasos/metabolismo; Proteínas de Homeodominio/metabolismo; Proteínas de Neoplasias/metabolismo; Neoplasias de las Glándulas Salivales/metabolismo; Animales; Carcinoma Adenoide Quístico/genética; Carcinoma Adenoide Quístico/patología; Línea Celular Tumoral; Ácidos Grasos/genética; Proteínas de Homeodominio/genética; Humanos; Ratones; Invasividad Neoplásica; Metástasis de la Neoplasia; Proteínas de Neoplasias/genética; Neoplasias de las Glándulas Salivales/genética; Neoplasias de las Glándulas Salivales/patología

Palabras clave

PRRX1; free fatty acids (FFAs); metabolism; metastasis; salivary adenoid cystic carcinoma (SACC)

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de las Glándulas Salivales / Carcinoma Adenoide Quístico / Proteínas de Homeodominio / Reprogramación Celular / Ácidos Grasos / Transición Epitelial-Mesenquimal / Proteínas de Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Prolif Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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