Immune inhibitory function of bovine CTLA-4 and the effects of its blockade in IFN-Î³ production.

Watari, Kei; Konnai, Satoru; Maekawa, Naoya; Okagawa, Tomohiro; Suzuki, Yasuhiko; Murata, Shiro; Ohashi, Kazuhiko

Watari, Kei; Konnai, Satoru; Maekawa, Naoya; Okagawa, Tomohiro; Suzuki, Yasuhiko; Murata, Shiro; Ohashi, Kazuhiko.

Afiliación

Watari K; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, 060-0818, Japan.
Konnai S; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, 060-0818, Japan. konnai@vetmed.hokudai.ac.jp.
Maekawa N; Department of Advanced Pharmaceutics, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, 060-0818, Japan. konnai@vetmed.hokudai.ac.jp.
Okagawa T; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, 060-0818, Japan.
Suzuki Y; Department of Advanced Pharmaceutics, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, 060-0818, Japan.
Murata S; Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, 060-0818, Japan.
Ohashi K; Department of Advanced Pharmaceutics, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, 060-0818, Japan.

BMC Vet Res ; 15(1): 380, 2019 Oct 29.

Article en En | MEDLINE | ID: mdl-31665022

Asunto(s)

Antígeno CTLA-4/metabolismo; Interferón gamma/metabolismo; Animales; Anticuerpos; Antígeno B7-1; Antígeno B7-2; Células COS; Antígeno CTLA-4/genética; Bovinos; Chlorocebus aethiops; Regulación de la Expresión Génica/efectos de los fármacos; Regulación de la Expresión Génica/inmunología; Interferón gamma/genética; Leucocitos Mononucleares/efectos de los fármacos; Leucocitos Mononucleares/metabolismo; Proteínas Recombinantes

Palabras clave

BLV; CD80; CD86; CTLA-4; Cattle; IFN-Î³

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Interferón gamma / Antígeno CTLA-4 Límite: Animals Idioma: En Revista: BMC Vet Res Asunto de la revista: MEDICINA VETERINARIA Año: 2019 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido

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