Drug-Resistant E. coli Bacteremia Transmitted by Fecal Microbiota Transplant.
N Engl J Med
; 381(21): 2043-2050, 2019 11 21.
Article
en En
| MEDLINE
| ID: mdl-31665575
ABSTRACT
Fecal microbiota transplantation (FMT) is an emerging therapy for recurrent or refractory Clostridioides difficile infection and is being actively investigated for other conditions. We describe two patients in whom extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli bacteremia occurred after they had undergone FMT in two independent clinical trials; both cases were linked to the same stool donor by means of genomic sequencing. One of the patients died. Enhanced donor screening to limit the transmission of microorganisms that could lead to adverse infectious events and continued vigilance to define the benefits and risks of FMT across different patient populations are warranted.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Bacteriemia
/
Escherichia coli
/
Heces
/
Disbiosis
/
Trasplante de Microbiota Fecal
Tipo de estudio:
Etiology_studies
Límite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
N Engl J Med
Año:
2019
Tipo del documento:
Article