Huang-Lian-Jie-Du extract ameliorates atopic dermatitis-like skin lesions induced by 2,4-dinitrobenzene in mice via suppression of MAPKs and NF-&#954;B pathways.

Chen, Yunlong; Xian, Yan-Fang; Loo, Steven; Lai, Zhengquan; Chan, Wood Yee; Liu, Ling; Lin, Zhi-Xiu

Huang-Lian-Jie-Du extract ameliorates atopic dermatitis-like skin lesions induced by 2,4-dinitrobenzene in mice via suppression of MAPKs and NF-κB pathways.

Chen, Yunlong; Xian, Yan-Fang; Loo, Steven; Lai, Zhengquan; Chan, Wood Yee; Liu, Ling; Lin, Zhi-Xiu.

Afiliación

Chen Y; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, China; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China. Electronic address: chenyl@link.cuhk.edu.hk.
Xian YF; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, China; Brain Research Centre, School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China. Electronic address: lisaxian@cuhk.edu.hk.
Loo S; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, China. Electronic address: stevenderm@gmail.com.
Lai Z; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, China. Electronic address: cruise0303@gmail.com.
Chan WY; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, China. Electronic address: wy-chan@cuhk.edu.hk.
Liu L; Basic Medical School, Guizhou University of Chinese Medicine, Guizhou, China. Electronic address: liulinggzcm@yahoo.com.
Lin ZX; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, China; Brain Research Centre, School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China; Institute of Integrative Medicine, Faculty of Me

J Ethnopharmacol ; 249: 112367, 2020 Mar 01.

Article en En | MEDLINE | ID: mdl-31678637

Asunto(s)

Dermatitis Atópica/tratamiento farmacológico; Medicamentos Herbarios Chinos/farmacología; Proteínas Quinasas Activadas por Mitógenos/metabolismo; FN-kappa B/metabolismo; Extractos Vegetales/farmacología; Transducción de Señal/efectos de los fármacos; Enfermedades de la Piel/tratamiento farmacológico; Animales; Antiinflamatorios/farmacología; Citocinas/metabolismo; Dermatitis Atópica/metabolismo; Dinitrobencenos/farmacología; Eosinófilos/efectos de los fármacos; Eosinófilos/metabolismo; Femenino; Inflamación/tratamiento farmacológico; Inflamación/metabolismo; Mastocitos/efectos de los fármacos; Mastocitos/metabolismo; Ratones; Ratones Endogámicos BALB C; Piel/efectos de los fármacos; Piel/metabolismo; Enfermedades de la Piel/inducido químicamente; Enfermedades de la Piel/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

Atopic dermatitis; DNCB-Sensitized mouse; Huang-Lian-Jie-Du extract; MAPKs; NF-κB

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de la Piel / Medicamentos Herbarios Chinos / Extractos Vegetales / Transducción de Señal / FN-kappa B / Proteínas Quinasas Activadas por Mitógenos / Dermatitis Atópica Límite: Animals Idioma: En Revista: J Ethnopharmacol Año: 2020 Tipo del documento: Article Pais de publicación: Irlanda

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