Female reproductive health in cystic fibrosis.
J Cyst Fibros
; 18 Suppl 2: S95-S104, 2019 10.
Article
en En
| MEDLINE
| ID: mdl-31679735
ABSTRACT
Women with cystic fibrosis (CF) are living longer and healthier lives, and opportunities for childbearing are increasingly promising. However, this population can also face sexual and reproductive health concerns, including menstrual irregularities, unplanned pregnancies, infertility and pregnancy complications. Additionally, more women are entering menopause and are at risk for the consequences of estrogen deficiency. The exact mechanisms involved in female reproductive health conditions in CF are not clearly understood, but are thought to include cystic fibrosis transmembrane regulator (CFTR)-mediated abnormalities, changes in female sex hormones, and other CF health-related factors. In the era of CFTR modulator therapy, new data are necessary to understand the impact of CFTR modulation on contraceptive effectiveness, fertility, and pregnancy outcomes to help guide future clinical care. This article reviews the current scientific knowledge of major reproductive health issues for women with CF.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Complicaciones del Embarazo
/
Fibrosis Quística
/
Enfermedades de los Genitales Femeninos
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
J Cyst Fibros
Año:
2019
Tipo del documento:
Article