Impact of Increased Nuchal Translucency Values on Pregnancy Outcomes: A Tertiary Center Experience.
Fetal Pediatr Pathol
; 40(3): 189-197, 2021 Jun.
Article
en En
| MEDLINE
| ID: mdl-31696754
ABSTRACT
OBJECTIVE:
We evaluated the association of nuchal translucency (NT) values above 99th percentile with perinatal outcomes. Materials andmethods:
Singleton pregnancies with NT values above 99th percentile were investigated. Pregnancies were divided into 3 groups group 1, NT = 2.6-<3.5 mm; group 2, NT = 3.5-4.5 mm; and group 3, NT > 4.5 mm. Demographic features, clinical characteristics, structural/chromosomal anomaly rates and perinatal outcomes were compared.Results:
Normal ultrasonographic anatomy was found in 47.5%, 7.7%, and 14.3% of groups 1, 2, and 3, respectively (p = 0.006). Group 3 had the lowest normal karyotype rate (44.6%) (p = 0.005). Higher frequencies for both miscarriage and pregnancy termination were observed in group 3 compared to group 1 (8.9% vs. 4.9% and 66.1% vs. 32.7%, respectively) (p = 0.02). The lowest rate of normal postnatal anatomic findings was found in group 3 (10.7%) (p = 0.01).Conclusion:
NT values above 99th percentile for gestational age seem to be associated with increased rates of chromosomal/structural abnormalities and adverse perinatal outcomes.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Resultado del Embarazo
/
Medida de Translucencia Nucal
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Fetal Pediatr Pathol
Asunto de la revista:
PATOLOGIA
/
PEDIATRIA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Turquía