Lower LINE-1 methylation is associated with promoter hypermethylation and distinct molecular features in gastric cancer.

Tahara, Sayumi; Tahara, Tomomitsu; Horiguchi, Noriyuki; Okubo, Masaaki; Terada, Tsuyoshi; Yoshida, Dai; Funasaka, Kohei; Nakagawa, Yoshihito; Shibata, Tomoyuki; Tsukamoto, Tetsuya; Ohmiya, Naoki

Tahara, Sayumi; Tahara, Tomomitsu; Horiguchi, Noriyuki; Okubo, Masaaki; Terada, Tsuyoshi; Yoshida, Dai; Funasaka, Kohei; Nakagawa, Yoshihito; Shibata, Tomoyuki; Tsukamoto, Tetsuya; Ohmiya, Naoki.

Afiliación

Tahara S; Diagnostic Pathology I, Fujita Health University School of Medicine, Toyoake, Japan.
Tahara T; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Horiguchi N; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Okubo M; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Terada T; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Yoshida D; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Funasaka K; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Nakagawa Y; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Shibata T; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.
Tsukamoto T; Diagnostic Pathology I, Fujita Health University School of Medicine, Toyoake, Japan.
Ohmiya N; Department of Gastroenterology, Fujita Health University School of Medicine, Toyoake, Japan.

Epigenomics ; 11(15): 1651-1659, 2019 11 01.

Article en En | MEDLINE | ID: mdl-31701771

Asunto(s)

Metilación de ADN/genética; Elementos de Nucleótido Esparcido Largo/genética; Regiones Promotoras Genéticas/genética; Neoplasias Gástricas/genética; Anciano; Islas de CpG/genética; Femenino; Mucosa Gástrica/microbiología; Regulación Neoplásica de la Expresión Génica/genética; Infecciones por Helicobacter/genética; Infecciones por Helicobacter/microbiología; Helicobacter pylori/patogenicidad; Humanos; Masculino; Fenotipo; Neoplasias Gástricas/microbiología

Palabras clave

CpG island methylator phenotype; Helicobacter pylori; LINE1; TP53 mutation; gastric cancer; genome-wide hypomethylation; molecular subtypes; promoter hypermethylation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Gástricas / Regiones Promotoras Genéticas / Metilación de ADN / Elementos de Nucleótido Esparcido Largo Tipo de estudio: Risk_factors_studies Límite: Aged / Female / Humans / Male Idioma: En Revista: Epigenomics Año: 2019 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido

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