TWIST1 transcriptionally regulates glycolytic genes to promote the Warburg metabolism in pancreatic cancer.

Wang, Xin-Xing; Yin, Guo-Qing; Zhang, Zhen-Hai; Rong, Zhong-Hou; Wang, Zhi-Yi; Du, Dong-Dong; Wang, Ya-Dong; Gao, Ru-Xin; Xian, Guo-Zhe

Wang, Xin-Xing; Yin, Guo-Qing; Zhang, Zhen-Hai; Rong, Zhong-Hou; Wang, Zhi-Yi; Du, Dong-Dong; Wang, Ya-Dong; Gao, Ru-Xin; Xian, Guo-Zhe.

Afiliación

Wang XX; Department of Hepatobiliary Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, 250021, Shandong Province, China.
Yin GQ; Department of General Surgery, Qingzhou People's Hospital, Qingzhou, 262500, Shandong Province, China.
Zhang ZH; Department of Hepatobiliary Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, 250021, Shandong Province, China.
Rong ZH; Department of Hepatobiliary Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, 250021, Shandong Province, China.
Wang ZY; Department of Hepatobiliary Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, 250021, Shandong Province, China.
Du DD; Department of Hepatobiliary Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, 250021, Shandong Province, China.
Wang YD; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Shangdong First Medical University, Jinan, 250014, Shandong Province, China.
Gao RX; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Shangdong First Medical University, Jinan, 250014, Shandong Province, China.
Xian GZ; Department of Hepatobiliary Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, 250021, Shandong Province, China. Electronic address: 18563715201@163.com.

Exp Cell Res ; 386(1): 111713, 2020 01 01.

Article en En | MEDLINE | ID: mdl-31705846

Asunto(s)

Adenocarcinoma/metabolismo; Regulación Neoplásica de la Expresión Génica; Glucólisis; Proteínas Nucleares/genética; Neoplasias Pancreáticas/metabolismo; Proteína 1 Relacionada con Twist/genética; Adenocarcinoma/genética; Adenocarcinoma/patología; Biomarcadores de Tumor/genética; Biomarcadores de Tumor/metabolismo; Proteínas Portadoras/genética; Proteínas Portadoras/metabolismo; Línea Celular Tumoral; Proteínas de Unión al ADN/genética; Proteínas de Unión al ADN/metabolismo; Transportador de Glucosa de Tipo 1/genética; Transportador de Glucosa de Tipo 1/metabolismo; Hexoquinasa/genética; Hexoquinasa/metabolismo; Humanos; Proteínas de la Membrana/genética; Proteínas de la Membrana/metabolismo; Neoplasias Pancreáticas/genética; Neoplasias Pancreáticas/patología; Fosfopiruvato Hidratasa/genética; Fosfopiruvato Hidratasa/metabolismo; Hormonas Tiroideas/genética; Hormonas Tiroideas/metabolismo; Proteínas Supresoras de Tumor/genética; Proteínas Supresoras de Tumor/metabolismo; Proteínas de Unión a Hormona Tiroide

Palabras clave

Extracellular acidification rate; Pancreatic cancer; TWIST1; Transcription factor; Warburg effect

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Proteínas Nucleares / Adenocarcinoma / Regulación Neoplásica de la Expresión Génica / Proteína 1 Relacionada con Twist / Glucólisis Límite: Humans Idioma: En Revista: Exp Cell Res Año: 2020 Tipo del documento: Article País de afiliación: China

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