HepG2-1A2 C2 and C7: Lentivirus vector-mediated stable and functional overexpression of cytochrome P450 1A2 in human hepatoblastoma cells.

Steinbrecht, Susanne; Pfeifer, Nadine; Herzog, Natalie; Katzenberger, Nadine; Schulz, Christian; Kammerer, Sarah; Küpper, Jan-Heiner

Steinbrecht, Susanne; Pfeifer, Nadine; Herzog, Natalie; Katzenberger, Nadine; Schulz, Christian; Kammerer, Sarah; Küpper, Jan-Heiner.

Afiliación

Steinbrecht S; Institute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Universitätsplatz 1, 01968 Senftenberg, Germany.
Pfeifer N; Institute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Universitätsplatz 1, 01968 Senftenberg, Germany.
Herzog N; Institute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Universitätsplatz 1, 01968 Senftenberg, Germany.
Katzenberger N; Institute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Universitätsplatz 1, 01968 Senftenberg, Germany.
Schulz C; Project Group Pz-Syn of the Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses IZI-BB, Am Mühlenberg 13, 14476 Potsdam, located at the Brandenburg University of Technology Cottbus-Senftenberg, Germany.
Kammerer S; Institute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Universitätsplatz 1, 01968 Senftenberg, Germany. Electronic address: sarah.kammerer@b-tu.de.
Küpper JH; Institute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Universitätsplatz 1, 01968 Senftenberg, Germany.

Toxicol Lett ; 319: 155-159, 2020 Feb 01.

Article en En | MEDLINE | ID: mdl-31706005

Asunto(s)

Citocromo P-450 CYP1A2/genética; Vectores Genéticos/genética; Hepatoblastoma/enzimología; Hepatoblastoma/genética; Lentivirus/genética; Neoplasias Hepáticas/enzimología; Neoplasias Hepáticas/genética; Aflatoxina B1/toxicidad; Línea Celular Tumoral; Citocromo P-450 CYP1A2/biosíntesis; Dermatoglifia del ADN/métodos; Humanos; Hígado/metabolismo; Mycoplasma/química; Fenacetina/farmacocinética; Plásmidos/genética

Palabras clave

CYP1A2; Cytochrome P450; HepG2; Liver metabolism

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hepatoblastoma / Lentivirus / Citocromo P-450 CYP1A2 / Vectores Genéticos / Neoplasias Hepáticas Límite: Humans Idioma: En Revista: Toxicol Lett Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Países Bajos

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