Polygenic risk score for disability and insights into disability-related molecular mechanisms.

Kulminski, Alexander M; Kang, Chansuk; Kolpakov, Stanislav A; Loika, Yury; Nazarian, Alireza; Yashin, Anatoliy I; Stallard, Eric; Culminskaya, Irina

Kulminski, Alexander M; Kang, Chansuk; Kolpakov, Stanislav A; Loika, Yury; Nazarian, Alireza; Yashin, Anatoliy I; Stallard, Eric; Culminskaya, Irina.

Afiliación

Kulminski AM; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, 27708-0408, USA. Alexander.Kulminski@duke.edu.
Kang C; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, 27708-0408, USA.
Kolpakov SA; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, 27708-0408, USA.
Loika Y; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, 27708-0408, USA.
Nazarian A; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, 27708-0408, USA.
Yashin AI; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, 27708-0408, USA.
Stallard E; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, 27708-0408, USA.
Culminskaya I; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, 27708-0408, USA.

Geroscience ; 41(6): 881-893, 2019 12.

Article en En | MEDLINE | ID: mdl-31707593

Asunto(s)

Envejecimiento/genética; Evaluación de la Discapacidad; Estudio de Asociación del Genoma Completo/métodos; Herencia Multifactorial/genética; Polimorfismo de Nucleótido Simple; Anciano; Alelos; Femenino; Genotipo; Humanos; Masculino; Persona de Mediana Edad; Fenotipo; Factores de Riesgo

Palabras clave

Biological function; Disability; Genetic architecture; Polygenic risk score

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Envejecimiento / Herencia Multifactorial / Polimorfismo de Nucleótido Simple / Evaluación de la Discapacidad / Estudio de Asociación del Genoma Completo Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Geroscience Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

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