Antimicrobial dosing in critical care: A pragmatic adult dosing nomogram.
Int J Antimicrob Agents
; 55(2): 105837, 2020 Feb.
Article
en En
| MEDLINE
| ID: mdl-31722224
ABSTRACT
Standard dosing of antimicrobials derived from product information is considered to have limited application in critically ill patients given the pharmacokinetic and pharmacodynamic changes often seen in these patients relative to other groups in the hospital. Dosing nomograms that account for the altered needs of critically ill patients are needed to minimise the likelihood of antimicrobial underdosing (risk of treatment failure) and overdosing (risk of toxicity) in these patients. The aim of this paper is to present a pragmatic, evidence-based, adult dosing nomogram for a selection of antimicrobials frequently prescribed to treat infections in critically ill patients.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Vancomicina
/
Beta-Lactamas
/
Nomogramas
/
Antibacterianos
Límite:
Humans
Idioma:
En
Revista:
Int J Antimicrob Agents
Año:
2020
Tipo del documento:
Article