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DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study.
Pickles, Jessica C; Fairchild, Amy R; Stone, Thomas J; Brownlee, Lorelle; Merve, Ashirwad; Yasin, Shireena A; Avery, Aimee; Ahmed, Saira W; Ogunbiyi, Olumide; Gonzalez Zapata, Jamie; Peary, Abigail F; Edwards, Marie; Wilkhu, Lisa; Dryden, Carryl; Ladon, Dariusz; Kristiansen, Mark; Rowe, Catherine; Kurian, Kathreena M; Nicoll, James A R; Mitchell, Clare; Bloom, Tabitha; Hilton, David A; Al-Sarraj, Safa; Doey, Lawrence; Johns, Paul N; Bridges, Leslie R; Chakrabarty, Aruna; Ismail, Azzam; Rathi, Nitika; Syed, Khaja; Lammie, G Alistair; Limback-Stanic, Clara; Smith, Colin; Torgersen, Antonia; Rae, Frances; Hill, Rebecca M; Clifford, Steven C; Grabovska, Yura; Williamson, Daniel; Clarke, Matthew; Jones, Chris; Capper, David; Sill, Martin; von Deimling, Andreas; Pfister, Stefan M; Jones, David T W; Hargrave, Darren; Chalker, Jane; Jacques, Thomas S.
Afiliación
  • Pickles JC; Developmental Biology and Cancer Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UK; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Fairchild AR; Developmental Biology and Cancer Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UK; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Stone TJ; Developmental Biology and Cancer Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UK; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Brownlee L; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Merve A; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Yasin SA; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Avery A; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Ahmed SW; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Ogunbiyi O; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Gonzalez Zapata J; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Peary AF; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Edwards M; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Wilkhu L; Specialist Integrated Haematology and Malignancy Diagnostic Service-Acquired Genomics, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Dryden C; Specialist Integrated Haematology and Malignancy Diagnostic Service-Acquired Genomics, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Ladon D; Specialist Integrated Haematology and Malignancy Diagnostic Service-Acquired Genomics, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Kristiansen M; UCL Genomics, UCL Great Ormond Street Institute of Child Health, London, UK.
  • Rowe C; Department of Neuropathology, North Bristol NHS Trust, Bristol, UK.
  • Kurian KM; Brain Tumour Research Centre, University of Bristol, UK.
  • Nicoll JAR; Cellular Pathology, University Hospital Southampton NHS Foundation Trust, Southampton, UK; BRAIN UK, Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
  • Mitchell C; BRAIN UK, Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
  • Bloom T; BRAIN UK, Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
  • Hilton DA; Cellular and Anatomical Pathology, University Hospitals Plymouth NHS Trust, Plymouth, UK.
  • Al-Sarraj S; Department of Clinical Neuropathology, Kings College Hospital NHS Trust, London, UK.
  • Doey L; Department of Clinical Neuropathology, Kings College Hospital NHS Trust, London, UK.
  • Johns PN; Department of Cellular Pathology, St George's University Hospital NHS Foundation Trust, London, UK.
  • Bridges LR; Department of Cellular Pathology, St George's University Hospital NHS Foundation Trust, London, UK.
  • Chakrabarty A; St James's University Hospital, The Leeds Teaching Hospitals NHS Trust, Leeds, UK.
  • Ismail A; St James's University Hospital, The Leeds Teaching Hospitals NHS Trust, Leeds, UK.
  • Rathi N; Department of Neuropathology, The Walton Centre NHS Foundation Trust, Liverpool, UK.
  • Syed K; Department of Neuropathology, The Walton Centre NHS Foundation Trust, Liverpool, UK.
  • Lammie GA; University Hospital of Wales, Cardiff, UK.
  • Limback-Stanic C; Department of Cellular Pathology, Imperial College Healthcare NHS Trust, London, UK.
  • Smith C; Western General Hospital, NHS Lothian, Edinburgh, UK.
  • Torgersen A; Western General Hospital, NHS Lothian, Edinburgh, UK.
  • Rae F; Western General Hospital, NHS Lothian, Edinburgh, UK.
  • Hill RM; Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Clifford SC; Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Grabovska Y; Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Williamson D; Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Clarke M; Division of Molecular Pathology, The Institute of Cancer Research, London, UK.
  • Jones C; Division of Molecular Pathology, The Institute of Cancer Research, London, UK.
  • Capper D; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Neuropathology, Berlin, Germany; German Cancer Consortium Partner Site Berlin, German Cancer Research Center, Heidelberg, Germany.
  • Sill M; Hopp Children's Cancer Center Heidelberg, Heidelberg, Germany.
  • von Deimling A; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany; Clinical Cooperation Unit Neuropathology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany.
  • Pfister SM; Hopp Children's Cancer Center Heidelberg, Heidelberg, Germany; Department of Pediatric Oncology, Hematology, Immunology, and Pulmonology, University Hospital Heidelberg, Heidelberg, Germany; Division of Pediatric Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Ger
  • Jones DTW; Hopp Children's Cancer Center Heidelberg, Heidelberg, Germany; Pediatric Glioma Research Group, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany.
  • Hargrave D; Developmental Biology and Cancer Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UK.
  • Chalker J; Specialist Integrated Haematology and Malignancy Diagnostic Service-Acquired Genomics, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Jacques TS; Developmental Biology and Cancer Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UK; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK. Electronic address: t.jacques@ucl.ac.uk.
Lancet Child Adolesc Health ; 4(2): 121-130, 2020 02.
Article en En | MEDLINE | ID: mdl-31786093
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regulación Neoplásica de la Expresión Génica / Neoplasias del Sistema Nervioso Central / Metilación de ADN / Terapia Molecular Dirigida Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Child / Humans Idioma: En Revista: Lancet Child Adolesc Health Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regulación Neoplásica de la Expresión Génica / Neoplasias del Sistema Nervioso Central / Metilación de ADN / Terapia Molecular Dirigida Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Child / Humans Idioma: En Revista: Lancet Child Adolesc Health Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido