Characterization and modeling of acousto-optic signal strengths in highly scattering media.
Biomed Opt Express
; 10(11): 5565-5584, 2019 Nov 01.
Article
en En
| MEDLINE
| ID: mdl-31799031
ABSTRACT
Ultrasound optical tomography (UOT) is an imaging technique based on the acousto-optic effect that can perform optical imaging with ultrasound resolution inside turbid media, and is thus interesting for biomedical applications, e.g. for assessing tissue blood oxygenation. In this paper, we present near background free measurements of UOT signal strengths using slow light filter signal detection. We carefully analyze each part of our experimental setup and match measured signal strengths with calculations based on diffusion theory. This agreement between experiment and theory allows us to assert the deep tissue imaging potential of â¼ 5 cm for UOT of real human tissues predicted by previous theoretical studies [Biomed. Opt. Express8, 4523 (2017)] with greater confidence, and indicate that future theoretical analysis of optimized UOT systems can be expected to be reliable.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Biomed Opt Express
Año:
2019
Tipo del documento:
Article
País de afiliación:
Suecia