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Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1-2 trial.
Geoerger, Birgit; Kang, Hyoung Jin; Yalon-Oren, Michal; Marshall, Lynley V; Vezina, Catherine; Pappo, Alberto; Laetsch, Theodore W; Petrilli, Antonio S; Ebinger, Martin; Toporski, Jacek; Glade-Bender, Julia; Nicholls, Wayne; Fox, Elizabeth; DuBois, Steven G; Macy, Margaret E; Cohn, Susan L; Pathiraja, Kumudu; Diede, Scott J; Ebbinghaus, Scot; Pinto, Navin.
Afiliación
  • Geoerger B; Department of Paediatric and Adolescent Oncology, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France. Electronic address: birgit.geoerger@gustaveroussy.fr.
  • Kang HJ; Department of Pediatrics, Seoul National University College of Medicine, Seoul National University Cancer Institute, Seoul National University Children's Hospital, Jongno-gu, Seoul, South Korea.
  • Yalon-Oren M; Pediatric Hemato-Oncology Department, Sheba Medical Center at Tel HaShomer, Ramat Gan, Israel.
  • Marshall LV; Paediatric and Adolescent Oncology Drug Development, The Royal Marsden Hospital and the Institute of Cancer Research, Sutton, UK.
  • Vezina C; Pediatric Oncology, McGill University Health Centre, Montréal, QC, Canada.
  • Pappo A; Oncology Department, St Jude Children's Research Hospital, Memphis, TN, USA.
  • Laetsch TW; Department of Pediatrics and Harold C Simmons Comprehensive Cancer Center, University of Texas Southwestern MedicalCenter/Children's Health, Dallas, TX, USA.
  • Petrilli AS; Federal University of São Paulo, Pediatric Oncology Institute (GRAACC-UNIFESP), São Paulo, Brazil.
  • Ebinger M; Department of Pediatric Hematology and Oncology, Children's University Hospital, Tübingen, Germany.
  • Toporski J; Department of Pediatrics, Skåne University Hospital, Lund, Sweden.
  • Glade-Bender J; Division of Pediatric Hematology and Oncology and Stem Cell Transplantation, Columbia University Medical Center, New York, NY, USA.
  • Nicholls W; Oncology Department, Lady Cilento Children's Hospital, South Brisbane, QLD, Australia.
  • Fox E; Developmental Therapeutics, Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • DuBois SG; Pediatric Hematology and Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.
  • Macy ME; Center for Cancer and Blood Disorders, Children's Hospital Colorado, Aurora, CO, USA.
  • Cohn SL; Department of Pediatrics, The University of Chicago Medicine, Chicago, IL, USA.
  • Pathiraja K; Department of Medical Oncology, Merck & Co, Kenilworth, NJ, USA.
  • Diede SJ; Department of Medical Oncology, Merck & Co, Kenilworth, NJ, USA.
  • Ebbinghaus S; Department of Medical Oncology, Merck & Co, Kenilworth, NJ, USA.
  • Pinto N; Hematology and Oncology, Seattle Children's Hospital, Seattle, WA, USA.
Lancet Oncol ; 21(1): 121-133, 2020 01.
Article en En | MEDLINE | ID: mdl-31812554
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Resistencia a Antineoplásicos / Anticuerpos Monoclonales Humanizados / Antígeno B7-H1 / Antineoplásicos Inmunológicos / Linfoma / Melanoma / Recurrencia Local de Neoplasia / Neoplasias Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Lancet Oncol Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Resistencia a Antineoplásicos / Anticuerpos Monoclonales Humanizados / Antígeno B7-H1 / Antineoplásicos Inmunológicos / Linfoma / Melanoma / Recurrencia Local de Neoplasia / Neoplasias Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Lancet Oncol Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido