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Integrin α6 signaling induces STAT3-TET3-mediated hydroxymethylation of genes critical for maintenance of glioma stem cells.
Herrmann, Andreas; Lahtz, Christoph; Song, Jieun; Aftabizadeh, Maryam; Cherryholmes, Gregory A; Xin, Hong; Adamus, Tomasz; Lee, Heehyoung; Grunert, David; Armstrong, Brian; Chu, Peiguo; Brown, Christine; Lim, Michael; Forman, Stephen; Yu, Hua.
Afiliación
  • Herrmann A; Department of Immuno-Oncology, Beckman Research Institute at City of Hope Comprehensive Cancer Center, Duarte, CA, 91010, USA. aherrmann@sorrentotherapeutics.com.
  • Lahtz C; Sorrento Therapeutics, San Diego, CA, 92121, USA. aherrmann@sorrentotherapeutics.com.
  • Song J; Department of Immuno-Oncology, Beckman Research Institute at City of Hope Comprehensive Cancer Center, Duarte, CA, 91010, USA.
  • Aftabizadeh M; Sorrento Therapeutics, San Diego, CA, 92121, USA.
  • Cherryholmes GA; Department of Immuno-Oncology, Beckman Research Institute at City of Hope Comprehensive Cancer Center, Duarte, CA, 91010, USA.
  • Xin H; Department of Immuno-Oncology, Beckman Research Institute at City of Hope Comprehensive Cancer Center, Duarte, CA, 91010, USA.
  • Adamus T; Department of Immuno-Oncology, Beckman Research Institute at City of Hope Comprehensive Cancer Center, Duarte, CA, 91010, USA.
  • Lee H; Department of Immuno-Oncology, Beckman Research Institute at City of Hope Comprehensive Cancer Center, Duarte, CA, 91010, USA.
  • Grunert D; Department of Immuno-Oncology, Beckman Research Institute at City of Hope Comprehensive Cancer Center, Duarte, CA, 91010, USA.
  • Armstrong B; Sorrento Therapeutics, San Diego, CA, 92121, USA.
  • Chu P; Department of Immuno-Oncology, Beckman Research Institute at City of Hope Comprehensive Cancer Center, Duarte, CA, 91010, USA.
  • Brown C; Department of Immuno-Oncology, Beckman Research Institute at City of Hope Comprehensive Cancer Center, Duarte, CA, 91010, USA.
  • Lim M; Department of Neuroscience, Beckman Research Institute at City of Hope Comprehensive Cancer Center, Duarte, CA, 91010, USA.
  • Forman S; Department of Pathology, City of Hope Comprehensive Cancer Center, Duarte, CA, 91010, USA.
  • Yu H; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope Comprehensive Cancer Center, Duarte, CA, 91010, USA.
Oncogene ; 39(10): 2156-2169, 2020 03.
Article en En | MEDLINE | ID: mdl-31819166
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Metilación de ADN / Integrina alfa6 / Epigénesis Genética / Dioxigenasas / Factor de Transcripción STAT3 / Glioma Límite: Animals / Female / Humans / Male Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Metilación de ADN / Integrina alfa6 / Epigénesis Genética / Dioxigenasas / Factor de Transcripción STAT3 / Glioma Límite: Animals / Female / Humans / Male Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido