A novel double-network antibacterial hydrogel based on aminated bacterial cellulose and schizophyllan.
Carbohydr Polym
; 229: 115383, 2020 Feb 01.
Article
en En
| MEDLINE
| ID: mdl-31826529
ABSTRACT
In this study, a novel hydrogel composed of bacterial cellulose (BC) and schizophyllan (SPG) biopolymers with improved mechanical, swelling and antibacterial properties was developed. BC was firstly functionalized using 3-aminopropyl triethoxysilane (APTES) to provide better interaction with SPG. A diffraction peak at 5.7° in the XRD pattern of amine-grafted BC/SPG membrane revealed the intercalation of SPG into BC network. SEM images of amine-grafted BC/SPG showed that the fibrillar network of BC was totally covered with schizophyllan. Two distinct stages of weight loss in TGA thermo-gram of amine grafted BC/SPG verified the successful entrance of SPG into BC fibrils. Tensile strength of the amine-grafted BC/SPG considerably increased to 42.19⯱â¯7.16â¯MPa as compared to neat BC (4.41 ± 0.38â¯MPa) and amine-grafted BC (7.90⯱â¯0.71â¯MPa). It also showed the highest swelling degree (800⯱â¯80%). Amine-grafted BC/SPG exhibited moderate antibacterial activity. MTT assay showed that amine-grafted BC/SPG stimulated the proliferation of normal human fibroblast cells.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Celulosa
/
Sizofirano
/
Hidrogeles
/
Antibacterianos
Límite:
Humans
Idioma:
En
Revista:
Carbohydr Polym
Año:
2020
Tipo del documento:
Article
País de afiliación:
Irán