Progerin-Induced Transcriptional Changes in Huntington's Disease Human Pluripotent Stem Cell-Derived Neurons.

Cohen-Carmon, Dorit; Sorek, Matan; Lerner, Vitaly; Divya, Mundackal S; Nissim-Rafinia, Malka; Yarom, Yosef; Meshorer, Eran

Cohen-Carmon, Dorit; Sorek, Matan; Lerner, Vitaly; Divya, Mundackal S; Nissim-Rafinia, Malka; Yarom, Yosef; Meshorer, Eran.

Afiliación

Cohen-Carmon D; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel.
Sorek M; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel.
Lerner V; The Edmond and Lily Safra Center for Brain Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel.
Divya MS; The Edmond and Lily Safra Center for Brain Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel.
Nissim-Rafinia M; Department of Neurobiology, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel.
Yarom Y; Department of Genetics, The Alexander Silberman Institute of Life Sciences, Edmond J. Safra Campus, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel.
Meshorer E; Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, 695011, Kerala, India.

Mol Neurobiol ; 57(3): 1768-1777, 2020 Mar.

Article en En | MEDLINE | ID: mdl-31834602

Asunto(s)

Enfermedad de Huntington/genética; Células Madre Pluripotentes Inducidas/metabolismo; Lamina Tipo A/metabolismo; Neuronas/citología; Células Madre Pluripotentes/metabolismo; Transcripción Genética; Diferenciación Celular/fisiología; Células Madre Embrionarias/metabolismo; Humanos; Proteína Huntingtina/genética; Proteína Huntingtina/metabolismo; Enfermedad de Huntington/metabolismo

Palabras clave

Embryonic stem cells; HD; Neuronal differentiation; Progerin; iPS cells; iPSC

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transcripción Genética / Enfermedad de Huntington / Células Madre Pluripotentes / Lamina Tipo A / Células Madre Pluripotentes Inducidas / Neuronas Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Mol Neurobiol Asunto de la revista: BIOLOGIA MOLECULAR / NEUROLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Israel Pais de publicación: Estados Unidos

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