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Identify old drugs as selective bacterial ß-GUS inhibitors by structural-based virtual screening and bio-evaluations.
Chen, Zhou; Xu, Xiaoshuang; Piao, Lianhua; Chang, Shan; Liu, Jiyong; Kong, Ren.
Afiliación
  • Chen Z; Institute of Bioinformatics and Medical Engineering, School of Electrical and Information Engineering, School of Chemical and Environmental Engineering, Jiangsu University of Technology, Changzhou, China.
  • Xu X; Institute of Bioinformatics and Medical Engineering, School of Electrical and Information Engineering, School of Chemical and Environmental Engineering, Jiangsu University of Technology, Changzhou, China.
  • Piao L; Institute of Bioinformatics and Medical Engineering, School of Electrical and Information Engineering, School of Chemical and Environmental Engineering, Jiangsu University of Technology, Changzhou, China.
  • Chang S; Institute of Bioinformatics and Medical Engineering, School of Electrical and Information Engineering, School of Chemical and Environmental Engineering, Jiangsu University of Technology, Changzhou, China.
  • Liu J; Department of Pharmacy, Fudan University Shanghai Cancer Center, Shanghai, China.
  • Kong R; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Chem Biol Drug Des ; 95(3): 368-379, 2020 03.
Article en En | MEDLINE | ID: mdl-31834987
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aspartame / Proteínas Bacterianas / Clozapina / Diarrea / Inhibidores Enzimáticos / Gemifloxacina / Glucuronidasa / Antidiarreicos Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Chem Biol Drug Des Asunto de la revista: BIOQUIMICA / FARMACIA / FARMACOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aspartame / Proteínas Bacterianas / Clozapina / Diarrea / Inhibidores Enzimáticos / Gemifloxacina / Glucuronidasa / Antidiarreicos Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Chem Biol Drug Des Asunto de la revista: BIOQUIMICA / FARMACIA / FARMACOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido