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The Meta-Position of Phe4 in Leu-Enkephalin Regulates Potency, Selectivity, Functional Activity, and Signaling Bias at the Delta and Mu Opioid Receptors.
Cassell, Robert J; Sharma, Krishna K; Su, Hongyu; Cummins, Benjamin R; Cui, Haoyue; Mores, Kendall L; Blaine, Arryn T; Altman, Ryan A; van Rijn, Richard M.
Afiliación
  • Cassell RJ; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, IN 47907, USA.
  • Sharma KK; Department of Medicinal Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
  • Su H; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, IN 47907, USA.
  • Cummins BR; Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA.
  • Cui H; College of Wuya, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Mores KL; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, IN 47907, USA.
  • Blaine AT; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, IN 47907, USA.
  • Altman RA; Department of Medicinal Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
  • van Rijn RM; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, IN 47907, USA.
Molecules ; 24(24)2019 Dec 12.
Article en En | MEDLINE | ID: mdl-31842282
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encefalina Leucina / Transducción de Señal / Receptores Opioides delta / Receptores Opioides mu Límite: Animals / Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encefalina Leucina / Transducción de Señal / Receptores Opioides delta / Receptores Opioides mu Límite: Animals / Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos